Ibuprofeno 500mg Para Que Sirve – Ibuprofen is a nonsteroidal anti-inflammatory drug derived from propionic acid (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. Naproxen belongs to the same drug class as ketoprofen, dexketoprofen, and flurbiprofen.
It has many pharmacological indications: it is used for the symptomatic treatment of fever and pain of mild to moderate intensity, as well as for the relief of symptoms in primary dysmenorrhea (pelvic pain and severe abdominal pain). flushing before or during menstruation). It is also used in the symptomatic treatment of arthritis (including juvenile rheumatoid arthritis), osteoarthritis, ankylosing spondylitis, and nonrheumatic arthritis.
Ibuprofeno 500mg Para Que Sirve
Ibuprofen requires a prescription in some cases. Judith Carrera from the Center for Drug Information (CIM) of the University of Pharmacists of Barcelona (COFB) explains this: “There are drugs on the market that require a prescription, like in all doses of medicine. . We see drugs with lower doses do not.”
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The 400 mg form, available over the counter, has been shown to be as effective as the higher dose for mild to moderate pain, but with fewer side effects.
Pharmacists recommend that this medication be used sensibly to minimize risks. “It is always recommended to use the lowest effective dose for the shortest period of time needed to relieve symptoms,” he said. The most common dose in adults is 400-600 mg every 6-8 hours and the maximum daily dose of 2400 mg should never be exceeded. “It can be taken with food to prevent digestive upset,” he says.
José Francisco Ávila de Tomas, a family physician at Santa Isabel Medical Center in Leganes (Madrid), notes that there are more reasons to prefer the 400-milligram dose in the elderly, because “they should only use it.” anti-inflammatory drugs in specific places”. and controlled cases due to their potential side effects.” .
For use in children, Avila notes that the ibuprofen dosage should be 20 or 30 milligrams per kilogram of body weight, divided into three or four doses per day. “It is indicated for 3 to 6 months, although it is not recommended to give it to children under one year of age more often,” he added.
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One of the most common doubts about antipyretic treatment is the ideal drug: ibuprofen or paracetamol. “In terms of drug treatment of fever, the two are interchangeable – Carrera addresses, although this also depends on the clinical condition of the patient.” For example: “In patients with contraindications to the use of NSAIDs, such as patients with bronchial asthma, chronic rhinitis, or allergic disease, as well as patients with peptic ulcer or coagulopathy, it is best to use paracetamol as an antipyretic.”
In children, ibuprofen can be used for children from 3 months of age and weighing more than 5 kg, and paracetamol can be used for children 3 to 32 kg (range 0-10 years).
Experts advise against alternating use of both drugs as an antipyretic strategy and suggest that “the use of one of the antipyretics should only be reserved for cases where fever cannot be reduced, as we never regularly recommended hours. We are not aware of the potential for side effects and medication errors.” increase the probability”.
Recently, Spain’s Agency for Medicines and Health Products (Aemps) has warned about the risk of using codeine and ibuprofen combinations for a long time or at higher than recommended doses. According to those responsible for the agency, “serious cases of renal, gastrointestinal and metabolic toxicity, some of which have resulted in death, have been linked to codeine abuse and dependence on medicine that contains a combination of codeine and ibuprofen.”
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Santolaya explains that warnings have been issued by European pharmacovigilance systems, but no cases have been reported in Spain, “in part because their use is more tightly controlled. here because these drugs can only be given with the right prescription.”
The most common adverse reactions of ibuprofen are those from the gastrointestinal tract (ulcer, heartburn, dyspepsia, gastrointestinal bleeding, esophagitis). However, other types of disorders have also been described:
“Adverse reactions can be minimized by using the lowest effective dose for the shortest possible time to control desired symptoms with ibuprofen,” Carrera states.
Nonsteroidal anti-inflammatory drugs, such as ibuprofen, can damage the stomach lining as a side effect. Concomitant consumption of alcohol increases this risk because it stimulates gastric acid secretion and can cause epigastric pain (stomach pain), heartburn (heartburn) and in severe cases, the pharmacy says. more important than ulcers and gastrointestinal bleeding”.
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A representative from the College of Pharmacists of Barcelona emphasized that there is no specific drug to treat a hangover, although both ibuprofen and paracetamol have been traditionally used to treat symptoms associated with excessive drinking. lots of alcohol; for example, to relieve headaches. In fact, “not recommended”. In the particular case of ibuprofen, you should avoid taking it immediately after drinking alcohol because it causes the aforementioned irritation to the digestive system.
Using nonsteroidal anti-inflammatory drugs such as ibuprofen in late pregnancy can cause premature closure of the ductus arteriosus (small vessel connecting the aorta to the pulmonary artery, which normally opens in the fetus but closes soon after birth). , oligohydramnios (lack of amniotic fluid surrounding the fetus) and neonatal anuria (no urine), so its use in the third trimester is contraindicated. However, a COFB representative commented that “since there is very little information about possible teratogenic effects (causing malformations in the fetus or fetus) during the first trimester, the general rule of thumb is to use NSAIDs as a general rule of thumb on NSAID use.” throughout pregnancy.
On the other hand, the use of this medication during breastfeeding is considered safe in women who are breastfeeding as long as it is not abused and the maximum daily intake and dosage recommendations are followed.
The expiration date shown on the package indicates the length of time the manufacturing laboratory can assure the effectiveness and safety of the drug, based on stability studies conducted during drug development. “After that date, the lab can’t guarantee that the drug is effective, so it’s generally not advisable to take any medication after the expiration date,” Santola notes. and non-steroidal anti-inflammatory drugs. IBUPROFEN Suspension LA SANTÉ® is indicated as an analgesic and antipyretic.
Ibuprofeno: Qué Es, Para Qué Sirve Y Efectos Secundarios
IBUPROFEN LA SANTÉ® is contraindicated in patients with known hypersensitivity to the active substance and/or salicylates and/or other non-steroidal anti-inflammatory drugs and/or any component of the formulation. Contraindicated in bronchospasm, acute rhinitis, nasal polyposis, angioedema, allergic reaction to acetylsalicylic acid or other NSAIDs, peptic ulcer, gastrointestinal bleeding, history of gastro-acid disease, severe liver dysfunction, first and third trimester of pregnancy. renal impairment (creatinine clearance < 30 ml/min), severe and moderate hepatic impairment. Treatment should be initiated and continued at the lowest therapeutic dose and for the shortest duration necessary.
The most frequently reported adverse events were gastrointestinal and central nervous system disturbances and hypersensitivity reactions. gastrointestinal upset, nausea, vomiting, diarrhea or constipation, abdominal distension, abdominal pain, peptic ulcer, gastrointestinal bleeding, headache, dizziness, palpitations, tinnitus, depression, somnolence, insomnia, hypersensitivity, bronchospasm, maculopapular rash, rash, pruritus, urticaria, angioedema), hepatotoxicity, visual disturbances (blurred vision, papilledema, effects optic nerve side effects), hematologic disorders (anemia, thrombocytopenia, neutropenia, agranulocytosis inhibition, thrombocytopenic purpura, thrombocytopenic purpura), renal disease , interstitial nephritis, nephrotic syndrome, hematuria, renal failure), fluid retention rarely leads to heart failure (especially in the elderly). Rarely, alveolitis, pulmonary eosinophilia, pneumonia, pancreatitis, purpura, aseptic meningitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, and life-threatening anaphylaxis network may occur.
The recommended dose of IBUPROFEN LA SANTÉ® for adults is 400-800 mg orally every 6-8 hours (maximum 3200 mg/day in divided doses). The recommended pediatric dose is 10 mg/kg/dose every 8 hours, oral IBUPROFEN LA SANTÉ® is contraindicated in patients with hypersensitivity to the active substance and/or salicylates and/or non-steroidal anti-infectives. is different. anti-inflammatory and/or with any ingredient in the formulation. Bronchospasm, acute rhinitis, nasal polyps, angioedema, allergic reaction to acetylsalicylic acid or other NSAIDs, peptic ulcer, gastrointestinal bleeding, history of peptic acid disease, liver dysfunction heavy,
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